Scouting runs are commonly used to evaluate sample purity after reactions using analytical HPLC. They are also used to calculate chromatography purification methods (ACS Combinatorial Science 2019, 21, 9, 609-613).
Join us for this free, 30-minute webinar, valuable to anyone interested in or using scouting gradients. While chromatography method development is commonly thought to be merely creating an efficient solvent system, many other details are needed to maximize sample recovery.
Who should attend
This webinar will be of interest to a large audience, as scouting runs can be run on different chromatography systems, including flash, preparative HPLC, and preparative SFC, as well as analytical systems.
What you’ll learn
- Will the compound run with a given solvent and column?
- A quick overview of how scouting gradients can be used to create efficient gradient methods.
- How peak shape indicates the need for a solvent modifier or additive
- How screening columns and solvents can improve resolution
- Improving detection parameters to improve recovery
- Suggestion of sample load
- For natural products, perform assay-directed method development
- Why use matching columns for method development?
Your presenter is chromatography specialist Jack Silver, an applications chemist with Teledyne LABS. You’ll have an opportunity to “ask the expert” questions specific to your applications. Questions we can’t get to during the webinar will be answered directly via email following the presentation.
